PK/PD Modelling & Simulation
At R-S-S, we specialise in Pharmacokinetic/Pharmacodynamic (Pop PK/PD) Modelling and Simulation, a critical aspect of drug development that helps in understanding the relationship between drug dosage, exposure, and therapeutic effects. Our advanced Pop PK/PD modelling and simulation services support the optimisation of dosing regimens, enhance the efficacy and safety of new therapeutics, and facilitate informed decision-making throughout the drug development process.
Our PK/PD Services
Bioavailability and Bioequivalence Studies
Drug Interaction Studies
Food Effect Studies
Dose Proportionality Assessment​
Phase I Dose Escalation Studies​
Pop PK Model Development​
Pop PK/PD Model Development​
Physiologically based PK/PD Models
(PB PK/PD Models)​
Dose-Response Modelling
(e.g. Emax modelling)​
​Model-Based Drug Development (MBDD)​
Simulations for Dose Optimisation​
Biomarker Identification and Validation​
Preparation and submission of PK/PD reports
Models for Regulatory Authorities ​​​​​​​​​​​​​​
Software Tools
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Expertise in the following Software: WinNonlin®, NONMEM®, SAS®, R, Simcyp™
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