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PK/PD Modelling & Simulation

At R-S-S, we specialise in Pharmacokinetic/Pharmacodynamic (Pop PK/PD) Modelling and Simulation, a critical aspect of drug development that helps in understanding the relationship between drug dosage, exposure, and therapeutic effects. Our advanced Pop PK/PD modelling and simulation services support the optimisation of dosing regimens, enhance the efficacy and safety of new therapeutics, and facilitate informed decision-making throughout the drug development process.

Our PK/PD Services

Bioavailability and Bioequivalence Studies

Drug Interaction Studies

Food Effect Studies

Dose Proportionality Assessment​

Phase I Dose Escalation Studies​

Pop PK Model Development​

Pop PK/PD Model Development​

Physiologically based PK/PD Models

(PB PK/PD Models)​

Dose-Response Modelling

(e.g. Emax modelling)​

​Model-Based Drug Development (MBDD)​

Simulations for Dose Optimisation​

Biomarker Identification and Validation​

Preparation and submission of PK/PD reports

Models for Regulatory Authorities â€‹â€‹â€‹â€‹â€‹â€‹â€‹â€‹â€‹â€‹â€‹â€‹â€‹â€‹

Software Tools

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Expertise in the following Software: WinNonlin®, NONMEM®, SAS®, R, Simcyp™

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